Clinical evidence

Atos Medical has a long standing tradition of clinical evidence showing that our products perform well and are safe to use. Over the years, many studies have been performed with our products and we are proud to say that we have more and stronger evidence for our products than any of our competitors.

We continually initiate or participate in clinical studies all over the world. This is made possible through our close cooperation with ENT specialists and patients. Take our Provox voice prostheses for laryngectomees, for instance. The Provox System has been a success from the start and this success is supported by a long list of peer-reviewed clinical documentation.

The Kelley Circuit

We are pleased to be able to share information about the Kelley Circuit with you. The Kelley Circuit is a novel method of managing in-hospital self-ventilating tracheostomy patients that allows for humidification, filtration and closed-circuit suctioning.


Humidification and filtration upon inspiration (protection for patient) Filtration upon expiration (protection for the health care professional) Closed-circuit and sterile suctioning (protection for patient and health care professional)

The document is authored by James Kelley et al. from the Wellington Hospital in London, UK and contains a description of the solution, a link to a Download our pdf here.

Please note that Atos Medical cannot give medical or clinical advice. Physicians and other health care providers reading this message should make independent, informed decisions about the care of their patients based on the individual condition and circumstances of each case. Always read the product instructions for use.


For a more detailed overview of all relevant publications on HMEs, Voice Prostheses and TheraBite, our Literature Reviews can be used. These are updated yearly.

Pulmonary rehabilitation
Pulmonary function with a tracheostoma
Benefits of HME use
Clinical effects
Attachment methods

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Provox Voice Prostheses
The product range
Clinical evidence about Provox voice prostheses
Microbiological studies

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Clinical Evidence Series

The Clinical Evidence Series are documents on a specific topic, describing and summarizing the most relevant literature. Download one of our documents from our Clinical Evidence Series below.

Importance of Compliant HME Use
Post-laryngectomy pulmonary symptoms
Pulmonary rehabilitation with HME
Improving compliant HME use

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Primary vs Delayed VP fitting
Comparison of primary and delayed voice prosthesis fitting
Evaluation of TE puncture with primary voice prosthesis fitting
Tracheoesophageal puncture stability and resizing

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Primary vs Secondary TEP
Comparison of primary and secondary TEP
Primary puncture and pharyngocutaneous fistulae

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Incidence of reflux in laryngectomees
Consequences and treatment of reflux in laryngectomees

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Early oral feeding
Advantages of early oral feeding
Pharyngocutaneous fistula (PCF) formation and feeding after total laryngectomy
Table of PCF rates in comparative studies of patients receiving early vs. late oral feeding

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